Logo der Universität Wien


Meshcheryakova A, Svoboda M, Tahir A, Köfeler HC, Triebl A, Mungenast F, Heinze G, Gerner C, Zimmermann P, Jaritz M, Mechtcheriakova D. Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach. Oncotarget. 2016 Mar 7. [Epub ahead of print]

Slany A, Bileck A, Kreutz D, Mayer RL, Muqaku B, Gerner C. Contribution of human fibroblasts and endothelial cells to the Hallmarks of Inflammation as determined by proteome profiling. Mol Cell Proteomics. 2016 Mar 29. [Epub ahead of print]  

Gschwandtner M, Paulitschke V, Mildner M, Brunner PM, Hacker S, Eisenwort G, Sperr WR, Valent P, Gerner C, Tschachler E. Proteome-analysis identifies L1CAM / CD171 and DPP4 / CD26 as novel markers of human skin mast cells. Allergy. 2016 Apr 19 [Epub ahead of print]

Šmidák R, Mayer RL, Bileck A, Gerner C, Mechtcheriakova D, Stork O, Lubec G, Li L. Quantitative proteomics reveals protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse. Behav Brain Res. 2015 Dec 31;303:208-217

Wolrab D, Frühauf P, Moulisová A, Kuchař M, Gerner C, Lindner W, Kohout M. Chiral separation of new designer drugs (Cathinones) on chiral ion-exchange type stationary phases. J Pharm Biomed Anal. 2016 Feb 20;120:306-15.  

Meier SM, Gerner C, Keppler BK, Cinellu MA, Casini A. Mass Spectrometry Uncovers Molecular Reactivities of Coordination and Organometallic Gold(III) Drug Candidates in Competitive Experiments That Correlate with Their Biological Effects. Inorg Chem. 2016 Feb 11. [Epub ahead of print]


Meier SM, Muqaku B, Ullmann R, Bileck A, Kreutz D, Mader JC, Knasmüller S, Gerner C. Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor Racemosus Secondary Metabolites Compared to Dexamethasone. PLoS One. 2015 Oct 23

Slany A, Bileck A, Muqaku B, Gerner C. Targeting breast cancer-associated fibroblasts to improve anti-cancer therapy. Breast. 2015 [Epub ahead of print]

Bileck A, Ferk F, Al-Serori H, Koller VJ, Muqaku B, Haslberger A, Auwärter V, Gerner C, Knasmüller S. Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage. Arch Toxicol 2015 [Epub ahead of print]

Muqaku B, Slany A, Bileck A, Kreutz D, Gerner C. Quantification of cytokines secreted by primary human cells using MRM: evaluation of analytical parameters. Anal Bioanal Chem. 2015 [Epub ahead of print]

Karlic H, Thaler R, Gerner C, Grunt T, Proestling K, Haider F, Varga F. Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. Cancer Genet. 2015 Mar 18 [Epub ahead of print]

Kaintz C, Mayer RL, Jirsa F, Halbwirth H, Rompel A. Site-directed mutagenesis around the CuA site of a polyphenol oxidase from Coreopsis grandiflora (cgAUS1). FEBS Lett. 2015 Feb 16 [Epub ahead of print]

Molitor C, Mauracher SG, Pargan S, Mayer RL, Halbwirth H, Rompel A Latent and active aurone synthase from petals of C. grandiflora: a polyphenol oxidase with unique characteristics Planta. 2015 Feb 20 [Epub ahead of print]

Paulitschke V, Berger W, Paulitscjke P, Hofstaetter E, Knapp B, Dingelmaier-Hovorka, Födinger D, Jäger W, Szekeres T, Meshcheryakova A, Bileck A, Pirker C, Pehamberger H, Gerner C, Kunstfeld R Vemurafenib resistance signature by proteome analysis offers new strategies and rational therapeutic concepts Mol Cancer Ther. 2015 Jan 22 [Epub ahead of print]


Baron DM, Kaindl U, Haudek-Prinz VJ, Bayer E, Röhrl C, Gerner C, Marian B. Autonomous inhibition of apoptosis correlates with responsiveness of colon carcinoma cell lines to ciglitazone. PLoS One. 2014 Dec 11;9(12).  

Bileck A, Kreutz D, Muqaku B, Slany A, Gerner C. Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells. J Proteome Res. 2014 Dec 5;13(12):5989-6000.  

Paulitschke V, Gerner C, Hofstätter E, Mohr T, Mayer R, Pehamberger H, Kunstfeld R Proteome profiling of keratinocytes transforming to malignancy. Electrophoresis. 2014 Nov 14. [Epub ahead of print]  

Veitinger M, Oehler R, Umlauf E, Baumgartner R, Schmidt G, Gerner C, Babeluk R, Attems J, Mitulovic G, Rappold E, Lamont J, Zellner M. A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype. Acta Neuropathol. 2014 Nov;128(5):665-77.  

Groessl M, Slany A, Bileck A, Gloessmann K, Kreutz D, Jaeger W, Pfeiler G, Gerner C. Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts. J Proteome Res. 2014 Nov 7;13(11):4773-82.  

Slany A, Meshcheryakova A, Beer A, Ankersmit HJ, Paulitschke V and Gerner C Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling Clinical Proteomics 2014, 11:41

Slany A, Paulitschke V, Haudek-Prinz V, Meshcheryakova A, Gerner C. Determination of cell type-specific proteome signatures of primary human leukocytes, endothelial cells, keratinocytes, hepatocytes, fibroblasts and melanocytes by comparative proteome profiling. Electrophoresis 2014, 35:1428-38.  

Zekiri F, Molitor C, Mauracher SG, Michael C, Mayer RL, Gerner C, Rompel A. Purification and characterization of tyrosinase from walnut leaves (Juglans regia). Phytochemistry. 2014, 101:5-15.  

Falsafi SK, Roßner S, Ghafari M, Groessl M, Morawski M, Gerner C, Lubec G. Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets. Amino Acids. 2014, 46:223-33  

Slany A, Haudek-Prinz V, Meshcheryakova A, Bileck A, Lamm W, Zielinski C, Gerner C, Drach J. Extracellular matrix remodeling by bone marrow fibroblast-like cells correlates with disease progression in multiple myeloma. J Proteome Res. 2014, 13:844-54


Slany A, Haudek-Prinz V, Zwickl H, Stättner S, Grasl-Kraupp B, Gerner C. Myofibroblasts are important contributors to human hepatocellular carcinoma: evidence for tumor promotion by proteome profiling. Electrophoresis 2013 34:3315-25

Klepeisz P, Sagmeister S, Haudek-Prinz V, Pichlbauer M, Grasl-Kraupp B, Gerner C. Phenobarbital induces alterations in the proteome of hepatocytes and mesenchymal cells of rat livers. PLOS ONE, 2013 8:e76137  

Paulitschke V, Haudek-Prinz V, Griss J, Berger W, Mohr T, Pehamberger H, Kunstfeld R, Gerner C. Functional classification of cellular proteome profiles support the identification of drug resistance signatures in melanoma cells. Journal of proteome research 2013 12: 3264-3276


Haudek-Prinz VJ, Klepeisz P, Slany A, Griss J, Meshcheryakova A, Paulitschke V, Mitulovic G, Stockl J, Gerner C. Proteome signatures of inflammatory activated primary human peripheral blood mononuclear cells. Journal of proteomics 2012 76 Spec No.: 150-162  

Weichhart T, Kopecky C, Kubicek M, Haidinger M, Doller D, Katholnig K, Suarna C, Eller P, Tolle M, Gerner C, Zlabinger GJ, van der Giet M, Horl WH, Stocker R, Saemann MD Serum amyloid A in uremic HDL promotes inflammation. Journal of the American Society of Nephrology JASN 201223: 934-947

Paulitschke V, Gruber S, Hofstatter E, Haudek-Prinz V, Klepeisz P, Schicher N, Jonak C, Petzelbauer P, Pehamberger H, Gerner C, Kunstfeld R. Proteome analysis identified the PPARgamma ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. PloS one 2012 7: e46103  

Zellner M, Baureder M, Rappold E, Bugert P, Kotzailias N, Babeluk R, Baumgartner R, Attems J, Gerner C, Jellinger K, Roth E, Oehler R, Umlauf E. Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients. Journal of proteomics 2012 75: 2080-2092  

Auerbach L, Rakus J, Bauer C, Gerner C, Ullmann R, Wimmer H, Huber J. Pomegranate seed oil in women with menopausal symptoms: a prospective randomized, placebo-controlled, double-blinded trial. Menopause 2012 19: 426-432  

Campregher C, Schmid G, Ferk F, Knasmuller S, Khare V, Kortum B, Dammann K, Lang M, Scharl T, Spittler A, Roig AI, Shay JW, Gerner C, Gasche C. MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells. PloS one 2012 7: e50541  

Veitinger M, Umlauf E, Baumgartner R, Badrnya S, Porter J, Lamont J, Gerner C, Gruber CW, Oehler R, Zellner M (2012) A combined proteomic and genetic analysis of the highly variable platelet proteome: from plasmatic proteins and SNPs. Journal of proteomics 2012 75: 5848-5860  

Distelmaier K, Adlbrecht C, Jakowitsch J, Wagner O, Gerner C, Lang IM, Kubicek M. Proteomic profiling of acute coronary thrombosis reveals a local decrease in pigment epithelium-derived factor in acute myocardial infarction. Clin Sci (Lond) 2012 123: 111-119


Griss J, Cote RG, Gerner C, Hermjakob H, Vizcaino JA. Published and perished? The influence of the searched protein database on the long-term storage of proteomics data. Molecular & cellular proteomics 2011 10: M111 008490  

Zellner M, Babeluk R, Jakobsen LH, Gerner C, Umlauf E, Volf I, Roth E, Kondrup J. A proteomics study reveals a predominant change in MaoB expression in platelets of healthy volunteers after high protein meat diet: relationship to the methylation cycle. J Neural Transm 2011 118: 653-662  

Griss J, Haudek-Prinz V, Gerner C GPDE: A biological proteomic database for biomarker discovery and evaluation. Proteomics 2011 11: 1000-1004  

Lyakhovich A, Michlmayr A, Bakulina A, Gerner C, Oehler R, Gasche C. Interaction of mesalasine (5-ASA) with translational initiation factors eIF4 partially explains 5-ASA anti-inflammatory and anti-neoplastic activities. Med Chem 2011 7: 92-98

Elbling L, Herbacek I, Weiss RM, Gerner C, Heffeter P, Jantschitsch C, Trautinger F, Grusch M, Pangratz H, Berger W. EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction. Toxicology letters 2011 205: 173-182  

Elbling L, Herbacek I, Weiss RM, Jantschitsch C, Micksche M, Gerner C, Pangratz H, Grusch M, Knasmuller S, Berger W (2010) Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes. Free radical biology & medicine 2011 49: 1444-1452


Gerner C, Haudek-Prinz VJ, Lackner A, Losert A, Peter-Vorosmarty B, Lorenz O, Grusch M. Indications for cell stress in response to adenoviral and baculoviral gene transfer observed by proteome profiling of human cancer cells. Electrophoresis 2010 31: 1822-1832  

Gerner C, Haudek V, Schandl U, Bayer E, Gundacker N, Hutter HP, Mosgoeller W () Increased protein synthesis by cells exposed to a 1,800-MHz radio-frequency mobile phone electromagnetic field, detected by proteome profiling. International archives of occupational and environmental health 2010 83: 691-702  

Slany A, Haudek VJ, Zwickl H, Gundacker NC, Grusch M, Weiss TS, Seir K, Rodgarkia-Dara C, Hellerbrand C, Gerner C. Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B. Journal of proteome research 2010 9: 6-21  

Distelmaier K, Adlbrecht C, Jakowitsch J, Winkler S, Dunkler D, Gerner C, Wagner O, Lang IM, Kubicek M (2009) Local complement activation triggers neutrophil recruitment to the site of thrombus formation in acute myocardial infarction. Thrombosis and haemostasis 2010 102: 564-572  

Paulitschke V, Schicher N, Szekeres T, Jager W, Elbling L, Riemer AB, Scheiner O, Trimurtulu G, Venkateswarlu S, Mikula M, Swoboda A, Fiebiger E, Gerner C, Pehamberger H, Kunstfeld R. 3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model. The Journal of investigative dermatology 2010 130: 1668-1679


Gundacker NC, Haudek VJ, Wimmer H, Slany A, Griss J, Bochkov V, Zielinski C, Wagner O, Stockl J, Gerner C Cytoplasmic proteome and secretome profiles of differently stimulated human dendritic cells. Journal of proteome research 2009 8: 2799-2811  

Ankersmit HJ, Hoetzenecker K, Dietl W, Soleiman A, Horvat R, Wolfsberger M, Gerner C, Hacker S, Mildner M, Moser B, Lichtenauer M, Podesser BK. Irradiated cultured apoptotic peripheral blood mononuclear cells regenerate infarcted myocardium. European journal of clinical investigation 2009 39: 445-456  

Hacker S, Lambers C, Pollreisz A, Hoetzenecker K, Lichtenauer M, Mangold A, Niederpold T, Hacker A, Lang G, Dworschak M, Vukovich T, Gerner C, Klepetko W, Ankersmit HJ. Increased soluble serum markers caspase-cleaved cytokeratin-18, histones, and ST2 indicate apoptotic turnover and chronic immune response in COPD. Journal of clinical laboratory analysis 2009 23: 372-379  

Haudek VJ, Slany A, Gundacker NC, Wimmer H, Drach J, Gerner C. Proteome maps of the main human peripheral blood constituents. Journal of proteome research 2009 8: 3834-3843  

Lorenz O, Parzefall W, Kainzbauer E, Wimmer H, Grasl-Kraupp B, Gerner C, Schulte-Hermann R. Proteomics reveals acute pro-inflammatory and protective responses in rat Kupffer cells and hepatocytes after chemical initiation of liver cancer and after LPS and IL-6. Proteomics Clinical applications 2009 3: 947-967

Paulitschke V, Kunstfeld R, Mohr T, Slany A, Micksche M, Drach J, Zielinski C, Pehamberger H, Gerner C Entering a new era of rational biomarker discovery for early detection of melanoma metastases: secretome analysis of associated stroma cells. Journal of proteome research 2009 8: 2501-2510  

Slany A, Haudek VJ, Gundacker NC, Griss J, Mohr T, Wimmer H, Eisenbauer M, Elbling L, Gerner C. Introducing a new parameter for quality control of proteome profiles: consideration of commonly expressed proteins. Electrophoresis 2009 30: 1306-1328  

Wimmer H, Gundacker NC, Griss J, Haudek VJ, Stattner S, Mohr T, Zwickl H, Paulitschke V, Baron DM, Trittner W, Kubicek M, Bayer E, Slany A, Gerner C. Introducing the CPL/MUW proteome database: interpretation of human liver and liver cancer proteome profiles by referring to isolated primary cells. Electrophoresis 2009 30: 2076-2089

Institut für Analytische Chemie
Universität Wien

Währinger Straße 38
A-1090 Wien
T: +43-1-4277-52301
F: +43-1-4277-9523
Universität Wien | Universitätsring 1 | 1010 Wien | T +43-1-4277-0